Table 2.
Multivariate regression analysis of childhood asthma in children with the GSTM1 null or positive genotype.
| GSTM1 null | GSTM1 positive | |||||
|---|---|---|---|---|---|---|
| P | OR | 95% CI | P | OR | 95% CI | |
| Male gender | 0.003 | 2.317 | 1.342–4.000 | 0.126 | 1.606 | 0.875–2.950 |
| Preterm (<37 weeks) | 0.583 | 0.725 | 0.230–2.285 | 0.723 | 0.784 | 0.205–2.999 |
| Maternal atopy† | 0.488 | 1.235 | 0.681–2.240 | 0.595 | 1.206 | 0.604–2.409 |
| Paternal atopy† | 0.228 | 1.419 | 0.803–2.509 | 0.125 | 1.643 | 0.871–3.101 |
| Prenatal TSE | 0.003 | 2.308 | 1.333–3.997 | 0.553 | 1.223 | 0.629–2.377 |
†Atopy is defined by phenotypic asthma, allergic rhinitis, or atopic dermatitis along with a detectable serum specific IgE (≥0.35 kU/L) response to one or more common allergens (egg white, cow's milk, peanut, shrimp, house dust mite, or German cockroach).