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. Author manuscript; available in PMC: 2015 Oct 6.
Published in final edited form as: Curr Biol. 2014 Sep 18;24(19):2295–2300. doi: 10.1016/j.cub.2014.08.017

Figure 3. Metacentrics have stronger centromeres relative to telocentrics in mice that have accumulated multiple metacentrics.

Figure 3

(A and B) Chromosome composition and HEC1 staining in CF-1 x CHPO MI oocytes (n=28). Staining was quantified at centromeres from CHPO telocentrics (identified as the dimmer kinetochores in bivalents, red asterisk) and from CHPO metacentrics in trivalents (yellow asterisk). (C) CENP-A staining in CHPO primary spermatocytes (n=67) was quantified for metacentrics (inset 1) and telocentrics (inset 2). Black asterisks: P<0.05; scale bars: 5 μm; AU: arbitrary units.