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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Pharmacogenet Genomics. 2014 Nov;24(11):564–574. doi: 10.1097/FPC.0000000000000086

Table 2.

Single nucleotide polymorphisms in SLC28A1 and related phenotypes

rsID Location/Effect Findings PMID
rs2242047 1528C>T (Arg51Cys) The CC genotype is associated with slower tumor progression compared to genotype TT in people with pancreatic cancer when treated with a combination of gemcitabine and erlotinib, or fluoropyrimidines. 22838950
rs2242047 1528C>T (Arg51Cys) The CC genotype is not associated with response, or risk of hematologic toxicity compared to genotypes CT and TT in people with NSCLC when treated with a combination of gemcitabine and carboplatin. 18538445
rs2242046 +1561 G>A (Asp521Asn) The GG genotype is associated with a decreased risk of hematologic toxicity compared to genotypes AG and AA in people with NSCLC, but is not associated with response to gemcitabine. 18538455

All alleles reported in the table are on the positive strand. Variants marked by an * are the complement of what is reported in the study.

Abbreviations: NSCLC (non-small cell lung cancer).