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. Author manuscript; available in PMC: 2015 Oct 7.
Published in final edited form as: Circulation. 2014 Aug 12;130(15):1274–1286. doi: 10.1161/CIRCULATIONAHA.114.006614

Figure 8.

Figure 8

Schematic representation of asTF signaling pathway. EC indicates endothelial cell; P-FAK, phosphorylated focal adhesion kinase; PI3K, phosphatidylinositol 3-kinase; Akt; MEK, mitogen-activated protein kinases; ERK, extracellular-signal-regulated kinases; HIF-1α, hypoxia-inducible factor-1α (inducible); HIF-1β, hypoxia-inducible factor-1β (constitutive); Ub, ubiquitin; VEGF165, vascular endothelial growth factor isoform 165 (soluble).