Table 1.
Patient characteristics.
| Characteristic | No. | % |
|---|---|---|
| Entire cohort | 87 | |
| Gender | ||
| Male | 65 | 75 |
| Female | 22 | 25 |
| Family status1 | ||
| Single | 20 | 23 |
| Married | 55 | 63 |
| Partner | 5 | 6 |
| Missing information | 7 | 8 |
| Karnofsky performance status | ||
| 90–100 | 31 | 36 |
| 70–80 | 30 | 34 |
| ≤60 | 26 | 30 |
| Primary tumor site | ||
| Prostate | 25 | 29 |
| Breast | 9 | 10 |
| Lung (non-small cell) | 10 | 11 |
| Colorectal | 8 | 9 |
| Bladder | 5 | 6 |
| Kidney | 6 | 7 |
| Skin (malignant melanoma) | 3 | 3 |
| Other | 21 | 24 |
| Dose/fractionation (intention-to-treat) | ||
| 10 fractions of 3 Gy | 24 | 28 |
| Single fraction of 8 Gy | 19 | 22 |
| 5 fractions of 4 Gy | 15 | 17 |
| 12–15 fractions of 2.5 Gy | 4 | 5 |
| Other | 25 | 29 |
| Reirradiation target types | ||
| Bone metastases | 69 | 79 |
| Brain metastases | 5 | 6 |
| Lung metastases or primary tumor | 6 | 7 |
| Other | 7 | 8 |
| Known brain metastases | ||
| No | 80 | 92 |
| One or more | 7 | 8 |
| Known liver metastases | ||
| No | 68 | 78 |
| One or more | 19 | 22 |
| Known lung metastases | ||
| No | 65 | 75 |
| One or more | 22 | 25 |
| Known adrenal gland metastases | ||
| No | 76 | 87 |
| One or more | 11 | 13 |
| Known bone metastases | ||
| No | 14 | 16 |
| One or more | 73 | 84 |
| Metastatic spinal cord compression | ||
| No | 80 | 92 |
| Yes (radiologic or symptomatic) | 7 | 8 |
| Pleural effusion | ||
| No | 81 | 93 |
| Yes (radiologic or symptomatic) | 6 | 7 |
| Number of metastatic sites | ||
| 0 | 10 | 11 |
| 1 (e.g., lungs only) | 37 | 43 |
| 2 (e.g., lungs and brain) | 27 | 31 |
| 3 | 11 | 13 |
| 4 | 2 | 2 |
| Progressive disease outside RT target volume1 | ||
| No | 27 | 31 |
| Yes | 55 | 63 |
| Missing information | 5 | 6 |
| Systemic cancer treatment1 | ||
| No | 23 | 26 |
| Within 4 weeks before RT | 21 | 24 |
| Within 3 months before RT | 14 | 16 |
| Earlier | 17 | 20 |
| Missing information | 12 | 14 |
| Use of opioid analgetics at start of RT1 | ||
| No | 21 | 24 |
| Yes | 54 | 62 |
| Missing information | 12 | 14 |
| Use of steroids at start of RT1 | ||
| No | 32 | 37 |
| Yes | 38 | 44 |
| Missing information | 17 | 20 |
| Serum hemoglobin1 | ||
| Low2 | 66 | 76 |
| Normal | 16 | 18 |
| Missing information | 5 | 6 |
| Serum albumin1 | ||
| Low2 | 17 | 20 |
| Normal | 42 | 48 |
| Missing information | 28 | 32 |
| Serum lactate dehydrogenase1 | ||
| Normal2 | 14 | 16 |
| Elevated | 35 | 40 |
| Missing information | 38 | 44 |
| Serum alkaline phosphatase1 | ||
| Normal2 | 25 | 29 |
| Elevated | 29 | 33 |
| Missing information | 33 | 38 |
| Serum creatinine1 | ||
| Low2 | 13 | 15 |
| Normal | 48 | 55 |
| Elevated | 15 | 17 |
| Missing information | 11 | 13 |
| Serum C-reactive protein1 | ||
| Normal2 | 20 | 23 |
| Elevated but less than 30 mg/L | 27 | 31 |
| Elevated 30–60 mg/L | 14 | 16 |
| Elevated >60 mg/L | 17 | 20 |
| Missing information | 9 | 10 |
| Thrombocyte count1 | ||
| Low2 | 11 | 13 |
| Normal | 45 | 52 |
| High | 19 | 22 |
| Missing information | 12 | 14 |
| Charlson comorbidity index1 | ||
| 0 | 7 | 8 |
| 1-2 | 44 | 51 |
| 3 or more | 28 | 32 |
| Missing information | 8 | 9 |
| Smoking status1 | ||
| Current smoker | 34 | 39 |
| No | 34 | 39 |
| Missing information | 19 | 22 |
RT: radiotherapy.
1Missing information in some cases.
2Hematology and blood chemistry results refer to institutional limits of normal; only test results obtained within one week before RT were considered.