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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Eur J Neurosci. 2014 Jul 16;40(7):3111–3119. doi: 10.1111/ejn.12675

Fig. 5. LIF induces Prdx4 mRNA transcript in OLs during OGD.

Fig. 5

Primary rat OL cultures were subjected to normoxia or OGD in the presence or absence of vehicle, 200 ng/ml LIF, or Akt IV. There were no significant differences in Prdx4 mRNA expression between any of the normoxic groups. Following OGD exposure, LIF-treated cells showed a significant increase in Prdx4 mRNA (*P<0.05, significant from OGD), and parallel cultures co-incubated with Akt IV showed Prdx4 mRNA levels that were significantly lower than cells treated with LIF alone (#P<0.05, significant from OGD+LIF). n=3 independent cultures. Norm, normoxia. OGD, oxygen glucose deprivation. LIF, leukemia inhibitory factor. Akt IV, Akt Inhibitor IV.