Table 2.
CST parameter before and 3months after CXL.
| Parameter (unit) | N | Before CXL | N | 3 months after CXL | P* | ||||
|---|---|---|---|---|---|---|---|---|---|
| Min/Max | Median (Q25/Q75) | Mean (±SD) | Min/Max | Median (Q25/Q75) | Mean (±SD) | ||||
| IOP (mmHg) | 17 | 7.50/17.00 | 11.00 (9.00/12.50) | 11.26 (2.76) | 17 | 8.00/45.50 | 14.00 (12.00/16.00) | 15.12 (8.31) | 0.004 † |
| pachy (µm) | 17 | 415/562 | 487 (473/539) | 498 (42.99) | 17 | 365 /548 | 452 (438 /502) | 463 (45.33) | <0.001 |
| defampmax (mm) | 17 | 0.94/1.41 | 1.18 (1.08/1.26) | 1.16 (0.13) | 17 | 0.44/1.51 | 1.09 (1.04/1.21) | 1.10 (0.22) | 0.155† |
| A1time (ms) | 17 | 6.49/7.50 | 6.93 (6.78/7.13) | 6.96 (0.28) | 17 | 6.61/10.68 | 7.12 (6.87/7.35) | 7.29 (0.92) | 0.024 † |
| A1length (mm) | 17 | 1.33/1.89 | 1.70 (1.53/1.79) | 1.65 (0.18) | 17 | 1.22/1.86 | 1.69 (1.60/1.76) | 1.64 (0.18) | 0.891 |
| A1velocity (ms) | 17 | 0.09/0.22 | 0.14 (0.13/0.17) | 0.15 (0.04) | 17 | 0.03/0.22 | 0.15 (0.13/0.17) | 0.15 (0.05) | 0.902 |
| A2time (ms) | 17 | 21.41/22.86 | 22.25 (21.84/22.46) | 22.16 (0.46) | 16 | 19.07/22.93 | 21.65 (21.54/21.95) | 21.66 (0.83) | 0.039 † |
| A2length (mm) | 17 | 0.80/2.41 | 1.27 (1.09/1.87) | 1.43 (0.47) | 17 | 0.78/2.12 | 1.55 (1.08/1.82) | 1.49 (0.44) | 0.702 |
| A2velocity (ms) | 17 | −0.67/−0.26 | −0.46 (−0.52/−0.39) | −0.45 (0.11) | 16 | −0.57/−0.24 | −0.44 (−0.49/−0.34) | −0.42 (0.10) | 0.348 |
| hctime (ms) | 17 | 16.17/18.25 | 17.09 (17.09/17.56) | 17.27 (0.50) | 17 | 15.25/18.71 | 17.09 (16.63/17.56) | 17.04 (0.77) | 0.292 |
| peakdist (mm) | 17 | 2.14/5.62 | 4.81 (4.68/5.10) | 4.46 (1.07) | 17 | 2.01/5.92 | 4.58 (2.49/5.08) | 3.97 (1.36) | 0.165 |
| radius (mm) | 17 | 4.27/9.48 | 5.80 (5.25/6.29) | 6.04 (1.27) | 17 | 4.52/9.96 | 6.04 (5.25/6.56) | 6.21 (1.41) | 0.488 |
| radius3p (mm) | 17 | 4.27/9.48 | 5.96 (5.30/6.35) | 6.12 (1.28) | 17 | 4.52/9.96 | 6.04 (5.25/6.56) | 6.23 (1.43) | 0.683 |
| A1deformationamp (mm) | 11 | 0.09/0.32 | 0.12 (0.10/0.15) | 0.14 (0.06) | 8 | 0.07/0.22 | 0.13 (0.11/0.18) | 0.14 (0.05) | 0.544 |
| hcdeformationamp (mm) | 11 | 0.99/1.55 | 1.14 (1.05/1.33) | 1.19 (0.18) | 8 | 0.95/1.41 | 1.14 (1.07/1.25) | 1.16 (0.15) | 0.838 |
| A2deformationamp (mm) | 11 | 0.18/0.53 | 0.38 (0.33/0.42) | 0.37 (0.09) | 7 | 0.21/0.44 | 0.38 (0.28/0.43) | 0.36 (0.08) | 0.270† |
| A1deflectionlength (mm) | 11 | 1.85/3.15 | 2.30 (2.02/2.46) | 2.32 (0.36) | 7 | 1.55/2.89 | 2.33 (2.06/2.79) | 2.38 (0.48) | 0.612† |
| hcdeflectionlength (mm) | 11 | 5.50/6.12 | 5.80 (5.75/6.03) | 5.85 (0.19) | 8 | 5.70/6.16 | 5.90 (5.78/5.96) | 5.89 (0.15) | 0.699 |
| A2deflectionlength (mm) | 10 | 1.90/3.63 | 3.00 (2.51/3.09) | 2.85 (0.48) | 5 | 2.05/3.50 | 3.12 (3.04/3.31) | 3.00 (0.56) | 0.095† |
| hcdeflectionamp (mm) | 11 | 0.81/1.36 | 0.97 (0.89/1.09) | 1.01 (0.17) | 11 | 0.75/1.36 | 0.97 (0.91/1.09) | 1.00 (0.17) | 0.592† |
| A1deflectionamp (mm) | 11 | 0.07/0.31 | 0.10 (0.07/0.11) | 0.11 (0.07) | 11 | 0.04/0.47 | 0.10 (0.07/0.18) | 0.14 (0.12) | 0.188 |
| A2deflectionamp (mm) | 11 | 0.03/0.33 | 0.13 (0.06/0.19) | 0.14 (0.09) | 11 | 0.00/0.69 | 0.15 (0.09/0.19) | 0.20 (0.20) | 0.247 |
| deflectionampmax (mm) | 11 | 0.81/1.40 | 0.98 (0.92/1.09) | 1.02 (0.17) | 8 | 0.76/1.26 | 1.00 (0.93/1.13) | 1.02 (0.16) | 0.885† |
| deflectionampmax (ms) | 11 | 15.99/16.83 | 16.40 (16.17/16.74) | 16.44 (0.31) | 8 | 14.35/17.20 | 15.99 (15.89/16.38) | 16.01 (0.81) | 0.254 |
P values reaching statistical significance are in bold font.
IOP: intraocular pressure; pachy: central corneal pachymetry; defampmax: maximum corneal deformation amplitude; A1time: time of the first applanation; A1length: Length of the first applanation; A1velocity: velocity of the corneal apex at the first applanation; A2time: time of the second applanation; A2length: length of the second applanation; A2velocity: velocity of the corneal apex at the second applanation; hctime: highest concavity, time of the maximum deformation; peakdist: distance between both non-deformed peaks; radius: radius of curvature at maximum deformation, calculated with “parabolic fit”; radius3p: radius of curvature at maximum deformation, 3-point-fit; A1deformationamp: deformation amplitude at the time of the first applanation; hcdeformationamp: deformation amplitude at the time of the highest concavity; A2deformationamp: deformation amplitude at the time of the second applanation; A1deflectionlength: deflection length at the time of the first applanation; hcdeflectionlength: deflection length at the time of the highest concavity; A2deflectionlength: deflection length at the time of the second applanation; hcdeflectionamp: deflection amplitude of the highest concavity; A1deflectionamp: deflection amplitude of the first applanation; A2deflectionamp: deflection amplitude of the second applanation; deflectionampmax (mm): maximum deflection amplitude; deflectionampmax (ms): time of the maximum deflection amplitude.
∗Paired t-test.
†Differences are not normally distributed. Therefore, Wilcoxon matched-pairs test was used.