Figure 5. Neither miR-155 overexpression nor MyD88 deficiency alters F. tularensis replication in human macrophages.
A–C. MDMs were infected with LVS (A), Schu S4 (B), or U112 (C) 48 h after transfection with miR-155-specific or negative control pre-miRs, and viable intracellular bacteria were quantified at the indicated time points by measurement of CFU. Data shown are the mean ±SEM (n = 3). D. LVS replicates normally in control (xBlue) and MyD88-deficient (x-Blue-def MyD88) THP-1 macrophages. Data are the mean ±SEM (n = 3).