Table 1. Differential expression of microRNAs in MDMs infected with F. tularensis LVS.
microRNAs | Fold changes | P values |
Down Regulated | ||
hsa-miR-197-4373102 | 0.3500 | 0.0134 |
Up Regulated | ||
hsa-miR-133a-4395357 | 1.5348 | 0.0017 |
hsa-miR-29c-4395171 | 1.6746 | 0.0226 |
hsa-miR-886-5p-4395304 | 1.6768 | 0.0417 |
hsa-miR-324-3p-4395272 | 1.6897 | 0.0349 |
hsa-miR-146a-4373132 | 1.7693 | 0.0181 |
has-miR-155-4395459 | 1.9780 | 0.0332 |
hsa-miR-126-4395339 | 2.0521 | 0.0186 |
hsa-miR-150-4373127 | 2.1002 | 0.0284 |
hsa-miR-361-5p-4373035 | 2.4114 | 0.0268 |
Differential expression analysis of microRNAs was carried out by TLDA (Applied Biosystems) using control MDMs and cells that were infected with LVS for 18 h. Average fold induction and P values were obtained from analysis of triplicate experiments. microRNAs that showed a fold change greater than 1.5 and p≤0.05 are shown.