Table 2.
MRI findings | Underlying pathophysiology | |
---|---|---|
1 | Hyperintensity on T2 weighted images | Edema and myelin damage |
2 | Hypointensity on T1 weighted images | Total loss of myelin with replacement of the region by a cyst |
3 | Hyperintense rims and hypointense cores on FLAIR images | Damage to the myelin at the rim with a central necrotic area |
4 | Uniformly hyperintense lesions on FLAIR | Mixture of demyelination and edema |
5 | Areas of restricted diffusion on DWI (acute phase) | Cytotoxic edema |