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. 2014 Sep 13;10:60. doi: 10.1186/1744-8069-10-60

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© Cahill et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Strain-related differences in BSCB permeability. Left panel shows normalized spine signal intensity in SNI (grey bars) and control (white bars) treatment groups at approximately 12 hours after surgery (n = 4–6 per group, except for CD-1: n = 2–3 per group). Right panel shows accumulation of Evans Blue dye in a separate cohort of SNI (grey bars) and control (white bars) treatment groups 24 hours after surgery (n = 5 per group). The mouse strains are ordered from least to most mechanical hypersensitivity after PNI. Data are presented as mean ± SEM; *p < 0.05 compared to controls.