Table 2. Laboratory parameters of bone and mineral metabolism and activated Vitamin D requirements.

	Treatment		Control		P-value*
	Baseline	12 Months	Baseline	12 Months
25OH-D,** ng/mL (median, [IQR])	13.5 [9.8, 20.9]	40.9 [32.2, 45.5]	13.0 [10.9, 20.4]	15.8 [9.5, 19.5]	<0.001
PTH, pg/mL	465.0 (360.5)	555.9 (436.6)	434.3 (380.7)	637.4 (645.5)	0.35
Calcium, mg/dL	9.2 (0.6)	9.0 (0.7)	8.8 (1.0)	9.0 (1.0)	0.09
Phosphorus, mg/dL	5.8 (1.2)	5.3 (1.4)	5.4 (1.8)	5.1 (1.4)	0.95
Activated Vitamin D dose, mcg/treatment (median, [IQR])	4.0 [0, 9.1]	4.0 [2.5, 5.0]	3.5 [0, 5.6]	5.0 [2.3, 7.5]	0.22

Mean (SD) unless otherwise specified.

*p-values for comparison of change from baseline to 12 months between groups (treatment vs control).

**n = 41 in treatment group and 27 in control group.