Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A proposed model of the role of Rx3 in early eye development. Rx3 functions to up-regulate pro-retinal genes and down-regulate pro-forebrain genes in the wild-types. Without the function of Rx3 (as indicated in the red dotted box), pro-retinal genes are not up-regulated and pro-forebrain genes are not repressed leading to a failure to properly form eyes and an expanded forebrain.
