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. 2014 Oct 8;9(10):e109600. doi: 10.1371/journal.pone.0109600

Table 5. Cox uni-and multivariable analysis of relative risk of death from non-mucinous colorectal cancer within 5 years by REG4 expression for patients under 65.

REG4 expression HR (95% CI) P-value N(events) HR (95% CI) P-value N(events)
Univariable Multivariable
Negative 1.00 228 (83) 1.00 227 (83)
Positive 0.57 (0.34–0.94) 0.029 76 (18) 0.55 (0.33–0.92) 0.022 76 (18)

Abbreviations: CI = confidence interval, HR = hazard ratio. Multivariable analysis included adjustment for gender, Dukes class, differentiation grade (G1/2 vs G3/4).