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. 2014 Sep 24;14:709. doi: 10.1186/1471-2407-14-709

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© Szulkin et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Correlation between proportion of effective drugs, percent malignant cells and survival time. Correlations of the proportion of effective drugs, drug efficiency, survival time, percent of malignant cells and sensitivity score plotted in A-D. Each data point in blue represents one patient, result from the linear regression analysis are presented in red. The drug efficiency is presented in red and adjusted drug efficiency in blue, with data points for each patient and linear regression analysis (E). Kaplan-Meier analysis presents survival time according to proportion of malignant cells in samples and proportion of effective drugs (F). Statistical significance was accepted at p < 0.05 and was seen for proportion of effective drugs and percent of malignant cells (A), proportion of effective drugs and survival time (C) and sensitivity score and survival time (D).