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. 2014 Sep 24;14:709. doi: 10.1186/1471-2407-14-709

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© Szulkin et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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RRM1 and ERCC1 immunoreactivity correlated to proportion of effective drugs and survival time. (A) Proportion of effective drugs plotted against RRM1 staining. (B) Survival time plotted against RRM1. (C) Proportion of effective drugs plotted against ERCC1 staining. (D) Survival time plotted against ERCC1 Regression analysis presented in red, data points for each patient in blue. Statistically significant departure of the slope from 0 was accepted at p < 0.05 and seen for proportion of effective drugs and RRM1 immunoreactivity (A).