Table 1.
Summary of relative risks of MCC occurring after solid organ transplantation.
| Reference | Study Type (Country) | Organ | No. of patients | No. of Patients With MCC | SIR or OR
95% confidence interval a |
|---|---|---|---|---|---|
| Buell et al. 2002 [71] | Multicenter (international) study (IPITTR) | Kidney, heart, liver | ≥15,000 OTR | 45 | -- |
| Baccarani et al. 2006 [79] | Single-center study (Italy) | Liver | 582 OTR (202 LTR) | 1 | -- |
| Koljonen et al. 2009 [27] | Registry analysis (Finland) | Kidney | 4200 RTR | 3 | SIR = 66 95% CI = 14–194 |
| Basic-Jukic et al. 2010 [80] | Single-center study (Croatia) | Kidney | 1232 RTR | 1 | -- |
| Kalinova et al. 2010 [81] | Single-center study (Czech Republic) | Kidney | 603 RTR | 1 | -- |
| Lanoy et al. 2010 [58] | Registry analysis (USA-SEER) ≥65 years old | Kidney, heart, lung, liver | 1286 OTR | 11 | OR = 4.95 95% CI = 2.62–9.34 |
| Na et al. 2013 [77] | Registry analysis (Australia) | Heart | 1,518 HTR | 17 | SIR = 103 95% CI = 60.4–166 |
Abbreviations: CI, confidence interval; HTR, heart transplant recipients; IPITTR, Israel Penn International Transplant Tumor Registry; LTR, liver transplant recipients; MCC, Merkel cell carcinoma; OR, odds ratio; OTR, organ transplant recipients; RTR, renal transplant recipients; recipients; SEER, Surveillance, Epidemiology, and End Results; SIR, standardized incidence ratio. a Statistically significant risk values are shown in boldface type.