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. 2014 Oct 2;11:86. doi: 10.1186/s12977-014-0086-8

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© De Feo et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Resistant Envs do not lose susceptibility to inhibition by N44 faster than WT. (A) Percent infectivity of pseudovirus on U87-CD4-CCR5 cells after addition of N44 at different time points. (B) Calculated T_1/2 of N44 susceptibility from time of addition experiments in (A). (C) Scatter plot correlating the T_1/2 of N44 susceptibility and the T_1/2 of fusion (Figure 3). *unpaired t-test indicates P values <0.05 showing longer time of susceptibility compared to WT. Linear regression and statistics for correlation is indicated. r_s, Spearman correlation coefficient.