Contact maps of ensembles without (upper left triangle) and with (lower right triangle) extrinsic chromophores for three proteins (left column) along with their native contacts (right column). (A) CSP, (B) LR, and (C) IN. Folded structures of each protein are shown in the left corner of native contacts maps; (yellow and magenta) secondary structures; and (gray sphere) C-terminal α-carbon atom of each protein. For native contact maps and structures, the Protein Data Bank entries PDB:1G6P (41), PDB:1LMB (42), and PDB:1WJA (43) were used for CSP, LR, and IN, respectively. To see this figure in color, go online.