Baseline values of distance, duration, and speed in control and experimental mice. A) Running wheel data at baseline for C57L/J mice (n=7) is shown. No differences in distance (km) (p=0.52), duration (mins) (p=0.52), or speed (m/min) (p=0.74) were found between control and experimental groups; however, C57L/J mice ran significantly farther, longer, and faster than C3H/HeJ mice at baseline (p<0.0001). B) Running wheel data at baseline for C3H/HeJ mice (n=8). No differences in distance (p=0.22), duration (p=0.23), or speed (p=0.44) were found between control and experimental groups.