Table II.

Duration and speed responses to dopaminergic drugs in C3H/HeJ mice.

Drug	Dose (mg/Kg)	Duration (mins/12hrs)		Speed (m/min)
		Control	Experimental	Control	Experimental
SKF 81297	0.5	97±106	73±33	15.2±4.8	17.2±2.6
	0.75	83±111	75±56	14.4±3.6	16.4±2.6
	1	101±145	103±56	14.5±4.2	16.5±2.8
	1.25	104±150	124±99	15.0±4.4	17.1±2.9
		p=0.95		p=0.11
SCH 23390	0.5	95±133	74±79	15.7±5.0	16.0±2.8
	0.75	110±141	84±78	15.3±5.5	16.3±2.5
	1	111±142	91±80	15.6±4.6	16.3±2.9
	1.25	110±147	89±80	15.5±5.6	16.1±2.6
		p=0.56		p=0.63
GBR 12783	15	20±16	66±41	12.5±1.4	16.3±1.7
	20	21±14	53±36	12.5±1.0	15.4±2.0
	25	19±12	69±25	12.1±1.2	16.4±1.8
	30	23±19	53±15	13.1±1.0	15.7±1.1
		p=0.0005*		p<0.0001*
AMPT	85	39±43	35±12	14.3±3.4	15.3±1.6
	90	34±32	36±6	14.4±2.9	15.0±1.3
	95	33±30	35±10	14.2±2.7	15.3±1.4
	100	29±26	37±15	15.3±3.0	15.5±1.6
		p=0.82		p=0.31

Duration and speed data for C3H/HeJ mice. p values reported indicate significant differences between groups within strain.