Figure 7.
Comparison of oblate and prolate spheroids. (A) Sketch of the two spheroids, parameterized by R1 and R2. For oblate spheroids (R1 > R2.), the lowest curvature region is the first to be engulfed, whereas for prolate spheroids (R1 < R2.), the highest curvature region is engulfed first. (B) Progression of engulfment with time. (Red) Oblate spheroid with R1 = R2 = 4.1 μm and R3 = 0.62 μm. (Blue) Prolate spheroid with R1 = R2 = 0.87 μm and R3 = 4 μm. (Solid lines) Full model with signaling; (dashed lines) pure diffusion model without signaling. (Solid circles) Half- and full engulfment. (Numbers) Order of engulfment. To see this figure in color, go online.