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. 2014 Sep 10;5(10):1124–1128. doi: 10.1021/ml500251z

Figure 2.

Figure 2

Coronal microPET images, time–activity curve, and blood clearance of [18F]FPTP or [13N]NH3 in normal rats after intravenous injection. (A) Images acquired after injection of 37 MBq of [18F]FPTP. (B) Images acquired after injection of 37 MBq of [13N]NH3. The heart was visible, with excellent heart-to-background contrast at each time point after [18F]FPTP injection. H, heart; L, liver; SUV, standardized uptake value. Time–activity curves generated from dynamic microPET images using (C) [18F]FPTP or (D) [13N]NH3. [18F]FPTP was retained at a constant level in the myocardium but was rapidly washed out from the liver and lungs. (E) Blood clearance of [18F]FPTP or [13N]NH3 in normal rats. The clearance half-time of [18F]FPTP and [13N]NH3 were less than 30 s, respectively. x-axis, SUV; y-axis, time (min).