Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. Author manuscript; available in PMC: 2014 Oct 9.

Published in final edited form as: Annu Res Rev Biol. 2013 Oct-Dec;3(4):323–349.

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 Parsons

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproductionin any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 1 — Covalent histone modification is a highly regulated process and directly linked to diverse biological functions, such as transcription regulation, cell cycle progress, and genomic imprinting. Histones are small highly conserved basic proteins. Histone modifications include acetylation, deacetylation, methylation, phosphorylation, and ubiquitylation; and mostly occur in the N-terminal tails that are highly K and R rich.