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Univariate and multivariate hazard ratio of Alzheimer's disease among carriers and noncarriers using affected and unaffected individuals. Blue dots represent hazard ratios from a univariate model and red dots represent hazard ratios from a multivariate model (SNP + sex + APOE). On y-axis, gene and mutation are presented; horizontal bars represent 95% confidence interval. For p.Glu318Gly variant in PSEN1, 95% confidence interval was truncated at 40.
