Table II.
Behavioral parameters recorded during the 90-second probe trial of the water maze (WM) test. Values represent mean ± SEM.
| Parameters | Control | LL |
|---|---|---|
| Target zone crossings | 5.1 ± 0.6 | 4.5 ± 0.5 |
| Swim speed | 25 ± 0.8 | 27 ± 0.7 |
| Distance | 2228 ± 72 | 2434 ± 59 |
| Activity | 78 ± 2 | 86 ± 1 |
| NW quadrant | ||
| LAT | 9 ± 3 | 6 ± 1 |
| FRQ | 7 ± 0.5 | 7 ± 0.4 |
| DUR | 22 ± 2 | 19 ± 0.3 |
| Distance | 481 ± 42 | 490 ± 23 |
| Activity | 75 ± 3 | 87 ± 3* |
| Target (SW) quadrant | ||
| LAT | 3 ± 0.4 | 5 ± 0.6 |
| FRQ | 9 ± 1 | 9 ± 0.6 |
| DUR | 36 ± 2 | 36 ± 1 |
| Distance | 742 ± 45 | 834 ± 37 |
| Activity | 78 ± 3 | 85 ± 1 |
| NE quadrant | ||
| FRQ | 6 ± 1 | 7 ± 0.3 |
| DUR | 14 ± 1 | 16 ± 1 |
| Distance | 367 ± 44 | 425 ± 20 |
| Activity | 79 ± 3 | 84 ± 1 |
| SE quadrant | ||
| LAT | 7 ± 2 | 5 ± 1 |
| FRQ | 7 ± 1 | 8 ± 0.4 |
| DUR | 18 ± 1 | 19 ± 1 |
| Distance | 421 ± 38 | 516 ± 27 |
| Activity | 82 ± 2 | 89 ± 3 |
* P < 0.05 compared to controls (Mann–Whitney U test). Twelve animals per group were tested, and the statistical analysis was based on number of litters (control group n = 12; LL-group n = 4).
Activity = percentage of time in the whole pool or a defined quadrant with swim speed of more than 2 cm/s; Distance = swim distance (cm); DUR = duration (s), total time spent in zone; FRQ = frequency, number of visits; LAT = latency (s), time to first visiting a zone; Swim speed = average swim speed (cm/s) in the pool; Target zone crossing = target zone (former location of the platform) crossings.