Table 2.
TMEM106A methylation status and Clinicopathological characteristics in gastric cancer
| TMEM106A methylation status | ||||
|---|---|---|---|---|
| Clinicopathological parameters | n | Methylated n = 93 (88.6%) | Unmethylated n = 12 (11.4%) | P-value |
| Age (years) | ||||
| <50 | 20 | 17 (85%) | 3 (15%) | 0.5787 |
| ≥50 | 85 | 76 (89.4%) | 9 (10.6%) | |
| Gender | ||||
| Male | 77 | 69 (89.6%) | 8 (10.4%) | 0.5808 |
| Female | 28 | 24 (85.7%) | 4 (14.3%) | |
| Alcohol abuse | ||||
| Negative | 75 | 68 (90.7%) | 7 (9.3%) | 0.2883 |
| Positive | 30 | 25 (83.3%) | 5 (16.7%) | |
| Smoking | ||||
| Negative | 71 | 66 (93.0%) | 5 (7.0%) | 0.0422* |
| Positive | 34 | 27 (79.4%) | 7 (20.6%) | |
| Differentiation | ||||
| Poor/Moderate | 95 | 84 (88.4%) | 11 (11.67%) | 0.5337 |
| Well | 3 | 3 (100.0%) | 0 (0.0%) | |
| T | ||||
| T2/T3 | 7 | 7 (100.0%) | 0 (0.0%) | 0.3276 |
| T4 | 98 | 86 (87.8%) | 12 (12.2%) | |
| N | ||||
| N0 | 17 | 13 (76.5%) | 4 (23.5%) | 0.0882 |
| N1/N2/N3 | 88 | 80 (90.9%) | 8 (9.1%) | |
| M | ||||
| M0 | 81 | 69 (85.2%) | 12 (14.8%) | 0.0462* |
| M1 | 24 | 24 (100.0%) | 0 (0.0%) | |
| TNM Stage | ||||
| II/III | 84 | 72 (85.7%) | 12 (14.3%) | 0.0670 |
| IV | 21 | 21 (100.0%) | 0 (0.0%) | |
*
P < 0.05.