Table 4.
Nephrotoxicity after cisplatin administration.
| CH (n = 17) | SH (n = 13) | P value | |
|---|---|---|---|
| AKI | |||
| Grade 1 | 1 | 2 | |
| Grade 2 | 0 | 0 | |
| >Grade 3 | 2† | 0 | |
| Creatinine increase | |||
| Grade 1 | 12 | 9 | |
| Grade 2 | 1 | 1 | |
| >Grade 3 | 2 | 0 | |
| I max (mg/dL) | 0.32 ± 0.57 | 0.14 ± 0.15 | 0.43 |
| D max (mg/min) | 18.3 ± 20.2 | 10.9 ± 13.3 | 0.28 |
Values are mean ± SD.
CH: continuous hydration.
SH: short hydration.
AKI: acute kidney injury.
I max: maximum creatinine increment.
D max: maximum clearance decrement.
†One patient discontinued treatment on account of nephrotoxicity.