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. 2014 Aug 12;11:39. doi: 10.1186/1550-2783-11-39

Table 3.

Serum cytokine concentrations

  PRE 30 min 60 min 90 min POST
IL-1β (pg/mL)
 
 
 
 
 
FA
0.9 ± 3.0
0.9 ± 2.5
1.0 ± 3.2
0.9 ± 2.8
0.7 ± 2.9
FC
0.9 ± 3.9
1.0 ± 4.9
1.0 ± 3.3
1.2 ± 3.7
1.4 ± 3.3
LA
0.9 ± 3.1
1.0 ± 2.8
0.8 ± 2.8
1.1 ± 3.0
1.1 ± 2.8
LC
1.2 ± 2.5
1.1 ± 2.7
0.9 ± 2.4
1.1 ± 2.7
1.3 ± 2.2
IL-1ra (pg/mL)
 
 
 
 
 
FA
186 ± 109
196 ± 131
203 ± 154
256 ± 77
267 ± 130
FC
159 ± 59
173 ± 51
234 ± 95
214 ± 121
212 ± 89
LA
203 ± 103
200 ± 100
202 ± 83
196 ± 61
269 ± 152
LC
234 ± 117
219 ± 138
209 ± 81
224 ± 125
177 ± 115
IL-6 (pg/mL)
 
 
 
 
 
FA
0.2 ± 1.5
0.1 ± 1.3
0.6 ± 2.3
2.6 ± 3.9a
6.3 ± 12.9b,d
FC
0.1 ± 0.5
0.2 ± 0.3
0.8 ± 1.5
1.9 ± 3.6
2.9 ± 8.8a,c
LA
0.2 ± 0.2
0.2 ± 0.1
0.5 ± 0.8
1.5 ± 4.0a
2.2 ± 9.2b,d
LC
0.2 ± 0.4
0.2 ± 0.2
0.9 ± 1.2
2.3 ± 2.0a,c
4.0 ± 6.6b,d
IL-8 (pg/mL)
 
 
 
 
 
FA
1.2 ± 0.5
1.5 ± 0.5
1.3 ± 0.7
1.7 ± 0.7
2.0 ± 0.9
FC
1.5 ± 0.5
1.3 ± 0.5
1.0 ± 0.4
1.5 ± 0.5
1.4 ± 0.6
LA
0.8 ± 0.4
1.1 ± 0.4
1.2 ± 0.7
1.2 ± 0.4
1.1 ± 0.5
LC
1.1 ± 0.4
1.5 ± 0.6
1.1 ± 0.5
1.6 ± 0.9
1.8 ± 0.7
IL-10 (pg/mL)
 
 
 
 
 
FA
5.3 ± 4.1
3.8 ± 3.8
5.1 ± 3.8
4.2 ± 1.6
2.8 ± 2.0
FC
2.6 ± 2.3
3.0 ± 5.0
3.2 ± 1.3
2.5 ± 2.7
2.9 ± 3.2
LA
4.5 ± 8.5
3.3 ± 2.4
3.5 ± 3.2
3.5 ± 3.0
4.9 ± 3.4
LC
3.4 ± 3.5
3.7 ± 3.5
3.9 ± 5.6
3.7 ± 2.4
3.4 ± 2.5
IL-12p40 (pg/mL)
 
 
 
 
 
FA
37 ± 8
44 ± 11
36 ± 6
38 ± 9
43 ± 5
FC
29 ± 5
36 ± 4
43 ± 8
27 ± 6
36 ± 6
LA
43 ± 7
37 ± 6
32 ± 4
30 ± 10
35 ± 5
LC
32 ± 8
32 ± 3
33 ± 3
30 ± 3
34 ± 4
Calprotectin (ng/mL)
 
 
 
 
 
FA
21 ± 14
26 ± 19
27 ± 24
47 ± 28
95 ± 147b
FC
18 ± 46
21 ± 121
25 ± 137
39 ± 196b
43 ± 267b,c
LA
23 ± 32
42 ± 29
62 ± 67
170 ± 181b
240 ± 117b,d
LC
26 ± 17
40 ± 45
60 ± 53
64 ± 42a
103 ± 276b,c
MPO (ng/mL)
 
 
 
 
 
FA
17 ± 2
20 ± 3
20 ± 1
27 ± 4
46 ± 11#
FC
20 ± 5
26 ± 8
25 ± 5
38 ± 13
39 ± 9#
LA
10 ± 2
26 ± 4
24 ± 2
34 ± 3
46 ± 5#
LC
17 ± 2
21 ± 3
19 ± 3
30 ± 7
34 ± 8#
TNF-α (pg/mL)
 
 
 
 
 
FA
0.3 ± 0.2
0.3 ± 0.1
0.3 ± 0.1
0.3 ± 0.1
0.4 ± 0.2
FC
0.3 ± 0.2
0.3 ± 0.2
0.3 ± 0.2
0.3 ± 0.1
0.3 ± 0.1
LA
0.3 ± 0.1
0.3 ± 0.1
0.3 ± 0.1
0.3 ± 0.1
0.3 ± 0.1
LC 0.3 ± 0.1 0.3 ± 0.1 0.2 ± 0.1 0.3 ± 0.1 0.3 ± 0.1

Data for IL-8, IL-12p40 and MPO are shown as mean ± SEM; data for IL-1β, IL-1ra, IL-6, IL-10, Calprotectin and TNF-α are shown as median ± quartile deviation aSignificantly different from PRE (P < 0.05). bSignificantly different from PRE (P < 0.01). cSignificantly different from 30 min (P < 0.05). dSignificantly different from 30 min (P < 0.01). #Main effect in time (P < 0.01).

Abbreviations: FA follicular phase placebo trial, FC follicular phase carbohydrate trial, IL interleukin, LA luteal phase placebo trial, LC luteal phase carbohydrate trial, MPO myeloperoxidase, POST high intensity time trial performance test, PRE before exercise, TNF tumor necrosis factor.