Table 4.
Primary and secondary outcomes comparison between groups at baseline and after 21 days on the prescribed diets
| Median [1 st -3 rd quartiles] |
Ma-Pi 2 diet (n = 25) |
Control diet (n = 26) |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | T21 | Absolute change | Percent change | Baseline | T21 | Absolute change | Percent change | p value* | |
|
Fasting blood glucose (mg/dl) |
129 (111; 149) |
95 (91; 100) |
34 (21; 44) |
26.2 (18.7; 34.1) |
126 (112; 150) |
110 (99; 115) |
22.8 (8.1; 44.6) |
16.9 (6.9; 30.1) |
0.073 |
|
Post prandial blood glucose (mg/dl) |
134 (112; 179) |
100 (94; 106) |
34 (18; 75.5) |
23.1 (15.9; 42.9) |
144 (128; 210) |
127 (108; 151) |
15.3 (−1.6; 58.6) |
8.7 (−1.9; 50.3) |
0.035 |
|
HbA
1c
(%) |
6.7 (6.2; 7.7) |
6.3 (5.9; 7) |
0.4 (0.2; 0.6) |
6.2 (3.3; 8.3) |
6.8 (6.4; 7.1) |
6.6 (6.2; 7) |
0.2 (0.1; 0.4) |
2.2 (1.5; 5) |
0.002 |
|
HOMA-IR |
3.1 (1.2; 4.1) |
0.98 (0.61; 1.98) |
1.3 (0.1; 2.9) |
51.4 (11.7; 78.3) |
3.3 (0.9; 4.6) |
1.6 (1.2; 2.4) |
1.4 (−0.2; 2.3) |
40.4 (−21.9; 62) |
0.142 |
|
Total cholesterol (mg/dl) |
176 (155; 217) |
120 (102; 138) |
57 (40; 65) |
32 (23.8; 38.6) |
180.5 (150.2; 210.8) |
154 (133; 185) |
24 (16; 43) |
12.3 (9.9; 23) |
< 0.001 |
|
LDL cholesterol (mg/dl) |
102 (84; 133) |
62 (39; 69) |
45 (33; 58) |
47.9 (33.5; 53.6) |
101.5 (84.8; 123.5) |
81 (66; 105) |
20 (12.3; 31.3) |
19.7 (13.5; 27.8) |
< 0.001 |
|
HDL cholesterol (mg/dl) |
46 (38; 52) |
42 (36; 51) |
4 (−1; 8) |
7.5 (−2.2; 17.1) |
48.5 (43; 55.8) |
47 (40; 56) |
0.5 (−2; 6.8) |
0.9 (−4.4; 11.5) |
0.283 |
|
LDL/HDL ratio |
2.4 (2; 3) |
1.3 (0.9; 2.4) |
0.9 (0.5; 1.3) |
38.5 (29.3; 49.9) |
2 (1.8; 2.6) |
1.8 (1.3; 2.4) |
0.4 (0.1; 0.7) |
17.2 (5.9; 29.5) |
< 0.001 |
|
BMI (kg/m
2
) |
31.3 (29.9; 36.8) |
29.5 (28.2; 34.6) |
2 (1.8; 2.4) |
5.9 (5.4; 6.9) |
32 (28.2; 35.9) |
30.8 (27.3; 34.6) |
1 (0.7; 1.3) |
2.9 (2.4; 4.1) |
< 0.001 |
|
Weight (kg) |
81.1 (75.6; 99.1) |
77 (70; 94) |
5.5 (4.4; 6) |
6.3 (5.6; 7.2) |
87 (79; 103.9) |
83 (75; 100) |
2.8 (2; 3.6) |
2.9 (2.4; 4.2) |
< 0.001 |
|
Waist circumference (cm) |
107.6 (97.9; 114.7) |
103 (96; 112) |
4.2 (1.4; 6.5) |
3.9 (1.6; 5.3) |
105.2 (101.6; 117.5) |
103 (101; 113) |
2.3 (0.9; 4) |
1.9 (0.9; 2.9) |
0.046 |
| Hip circumference (cm) | 108.7 (102.5; 23.8) | 105 (99; 120) | 3.4 (2; 5.2) | 3.1 (1.8; 4) | 109.7 (102.6; 118.4) | 108 (101; 118.4) | 1.8 (1; 2.5) | 1.6 (0.8; 2.4) | 0.006 |
Legend: *P-value by Wilcoxon rank-sum test are referred to percent changes between the two treatment groups.