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. 2014 Aug 28;11:40. doi: 10.1186/1743-7075-11-40

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Copyright © 2014 Nakamura et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Representative photomicrographs of the distal end of the maxilloturbinate in TDI-sensitized nasal allergy model rat. Hematoxylin and eosin stainig (Upper). The mucus secretion in the nasal cavity and epithelia was increased in the AL with TDI. Toluidine blue staining (Middle). The degranulated mast cells presented in lamina propria of nasal epithelia in the AL with TDI. Insets show the magnified images of mast cell. Immunohistochemical detection of mast cell tryptase (Lower). Tb: turbinate bone. C: nasal cavity E: nasal epithelium. Arrow: non-degranulated mast cell. Arrow head: degranulated mast cell.