FIGURE 1.

Mean MAL arm use scores from CI therapy (n = 21) and placebo control (n = 20) patients with chronic stroke. CI therapy subjects showed a very large improvement in arm use outside the laboratory from pretreatment to post-treatment (1.8 ± 0.6; P < 0.0001; d’ = 3.0). Before treatment the data indicate that these patients were using the more affected arm 14% as much as before stroke, while after 2 weeks of treatment it was 52%, an almost four times increase. Controls showed little change. CI therapy subjects retained all of their immediate treatment gains 4 weeks after therapy and showed only a 23% decrease after 2 years from post-treatment levels of real-world arm use. At 1-year post-treatment the loss in retention was 14%. Reprinted from Taub et al. (2006a).