Table 4.
Genotype and allelic population frequencies of SNPs found in ABCB1 and ABCC2 genes.
| Gene | SNP | NCBI assay ID | Population | Sample (2n) | Allele frequency | Genotype frequency |
|---|---|---|---|---|---|---|
| ABCB1 | rs2235048 | ss35072278 | Hispanic | 44 | T = 0.455 | TT = 0.182 |
| C = 0.545 | TC = 0.545 | |||||
| CC = 0.273 | ||||||
| ss48292340 | Hispanic | 38 | T = 0.553 | TT = 0.369 | ||
| C = 0.447 | TC = 0.368 | |||||
| CC = 0.263 | ||||||
| ss44833502 | Mexican | 100 | T = 0.540 | TT = 0.260 | ||
| C = 0.460 | TC = 0.560 | |||||
| CC = 0.180 | ||||||
| rs2235047 | ss35072277 | Hispanic | 44 | T = 0.932 | TT = 0.864 | |
| G = 0.068 | TG = 0.136 | |||||
| Mexican | 100 | T = 0.900 | TT = 0.840 | |||
| G = 0.100 | TG = 0.126 | |||||
| GG = 0.011 | ||||||
| ss48292339 | Hispanic | 42 | T = 0.952 | TT = 0.905 | ||
| G = 0.048 | TG = 0.095 | |||||
| GG = 0.00 | ||||||
| rs1045642 | ss35072275 | Hispanic | 42 | T = 0.452 | TT = 0.238 | |
| C = 0.548 | TC = 0.429 | |||||
| CC = 0.333 | ||||||
| Mexican | 100 | C = 0.540 | TT = 0.180 | |||
| T = 0.460 | TC = 0.560 | |||||
| CC = 0.260 | ||||||
| rs2214102 | ss12675208 | Hispanic | 46 | G = 0.957 | G/G = 0.913 | |
| A = 0.043 | A/G = 0.087 | |||||
| ss35071953 | Hispanic | 44 | G = 0.905 | G/G = 0.810 | ||
| A = 0.095 | A/G = 0.190 | |||||
| ss52073858 | Mexican | 77 | G = 0.980 | G/G = 0.960 | ||
| A = 0.020 | A/G = 0.040 | |||||
| rs2229109 | ss35072104 | Hispanic | 44 | G = 1.000 | G/G = 1.000 | |
| A = 0.000 | A/G = 0.000 | |||||
| ss48292345 | Hispanic | 46 | G = 0.978 | G/G = 0.957 | ||
| A = 0.022 | A/G = 0.043 | |||||
| rs1128503 | ss35072107 | Hispanic | 44 | T = 0.545 | C/T = 0.545 | |
| C = 0.455 | T/T = 0.273 | |||||
| C/C = 0.182 | ||||||
| ss48292343 | Hispanic | 46 | C = 0.609 | C/T = 0.522 | ||
| T = 0.391 | C/C = 0.348 | |||||
| T/T = 0.130 | ||||||
| ss52068966 | Mexican | 77 | C = 0.540 | C/T = 0.560 | ||
| T = 0.460 | C/C = 0.260 | |||||
| T/T = 0.180 | ||||||
| rs2032582 | ss12675210 | Hispanic | 46 | G = 0.565 | G/T = 0.522 | |
| T = 0.392 | G/G = 0.261 | |||||
| A = 0.043 | T/T = 0.130 | |||||
| A/G = 0.08 | ||||||
| ss35072218 | Hispanic | 44 | G = 0.545 | G/T = 0.636 | ||
| T = 0.455 | G/G = 0.227 | |||||
| T/T = 0.136 | ||||||
| ss12675210 | Mexican | 77 | G = 0.570 | G/T = 0.540 | ||
| T = 0.430 | G/G = 0.300 | |||||
| T/T = 0.160 | ||||||
| ABCC2 | rs3740066 | ss48292395 | M | 44 | C = 0.614 | C/T = 0.500 |
| T = 0.386 | C/C = 0.364 | |||||
| T/T = 0.136 |
Hispanic populations from ss12675208, ss48292345, ss48292343, ss12675210, and ss48292395 samples belong to HISP-MULTI-NATIONAL Population ID Class, obtained of 23 anonymized individuals of self-described HISPANIC heritage. Hispanic populations from ss35071953, ss35072104, ss35072107 and ss35072218 samples belong to EGP_HISP-PANEL Population ID Class, obtained of 22 individuals with Coriell Cell Repository (CCR) ID. Mexican population belongs to HAPMAP-MEX Population ID Class, obtained of 100 individuals with Mexican ancestry in Los Angeles, California.