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. 2014 Oct 9;5:474. doi: 10.3389/fimmu.2014.00474

Figure 1.

Figure 1

Age-dependent expression of innate immune receptors, signaling, and effector molecules in murine intestinal epithelial cells. (A) Innate immune receptors and inhibitory molecules. TLRs, blue; NLRs, green; RLRs, orange; negative regulators (SIGIRR, A20, PPARy, IRAK-M, IKK2), red. (B) Soluble intermediates: interleukins, blue; epithelial-derived modifiers of myeloid cells, red. (C) Antimicrobial effector molecules: (β-defensins, green; CRS peptides, blue; α-defensins (Defa), red; Reg3β/γ, Angiogenin4 (Ang4), and CRAMP, orange.