Figure 5.

Significant interactions involving the α-globin cluster for the K562 cell line. Chromosomal position is indicated on the top, with annotated genes shown in orange. Significant interactions from the NCHG test and Fisher's exact test are shown as connected segments. Significant interactions colored blue and red, for the NCHG test and Fisher's exact test, respectively, are verified using 5C data from Sanyal et al. (16). Gray segments indicate interactions that were not found in the 5C dataset. The position of three hypersensitivity sites (HS55, HS46 and HS40) found inside the NPRL3 gene are indicated using green shading.