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Codon optimization in bmrB leads to reduced transcription of bmrCD. A. Sequences of the bmrB (marked bmrB162) and bmrBCopt genes. The five rare codons that were mutated in bmrBCopt are marked with an asterisk (*). B. Maximum GFP expression values (AU) obtained from B. subtilis carrying pRM3-bmrB162 or pRM3-bmrBCopt in response to xylose induction, either with or without lincomycin (0.75 μg/ml).
