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. 2014 Oct 9;8:197. doi: 10.3389/fnsys.2014.00197

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Copyright © 2014 Ordek, Proddutur, Santhakumar, Pfister and Sahin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evoked potential waveform progression in a sample animal from the time of injury (A–F). Each trace represents the average of multiple trials (gray traces), and each trial is the stimulus (S, t = 0) trigger-average of 20 EPs. The black shade is the ± std. Mossy fiber-mediated potentials analyzed in Figure 2 are marked in similar manner (A, a-c; B–F, arrowheads). The pre-injury recordings were obtained 5–10 min before the application of FPI (A). Time of recording after anesthesia was ~5 min (A,C–F) and 5–10 min after FPI induction (B). All injury-day recordings showed great depression in the EP waveform and amplitudes. Day-3 EPs demonstrated larger amplitude variations; 5 ± 5 µV (D).