Table 4.
Thyroid Cancer-Specific Mortality and Hazard Ratios for Patients With TERT wt vs TERT Mutated Tumors
| Type of Cancer | Mortality, n, % |
Mortality Rate (Deaths per 1000 Person-Years) |
Hazard Ratio (95% CI) |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Overall | TERT wt | TERT Mutated | P Valuea | TERT wt | TERT Mutated | Unadjusted | P Value | Adjustedb | P Value | |
| DTC | 7/323 (2.2) | 3/298 (1.0) | 4/25 (16.0) | <.001 | 1.17 | 21.17 | 19.42 (4.30–87.64) | <.001 | 10.35 (2.01–53.24) | .005 |
| PTC | 5/284 (1.8) | 3/265 (1.1) | 2/19 (10.5) | .001 | 1.36 | 13.64 | 11.63 (1.93–70.15) | .007 | 23.81 (1.36–415.76) | .03 |
| FTC | 2/70 (2.8) | 0/58 | 2/12 (16.7) | <.001 | 0 | 47.23 | c | c | c | c |
Abbreviations: mut, mutated; wt, wild type.
a
Log-rank P values.
b
Adjusted for age and gender (Cox regression).
c
Due to the low numbers, a regression analysis was not performed for FTC patients.