Scheme 4. Synthesis of Analogues 72 and 77.
(a) N-butyllithium (2.0 equiv), triisopropyl borate (2.0 equiv) THF, −78 °C, 18 h; (b), 2 M Na2CO3 (4.0 equiv), DPP-Pd silica bound Silicycle 0.26 mmol/g (20 mol %), DME, MW, 150 °C, 30 min, 35–50% yield.
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