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Effect of SS application (∼50 μl, 25 mg/ml) to the cochlear round window membrane on the mean (±SEM) CAP (A) and AC LFP (B) input/output functions. The cochlear application of SS elevated threshold approximately 20 dB and reduced the amplitude of the CAP and AC LFP at all intensity levels. (C) Mean (±SEM, n=4) LFP input/output function from IC pre- and 1 h post systemic SS treatment (i.p. 250 mg/kg).
