Table 1.
Cases No. (%) |
Controls No. (%) |
|
---|---|---|
No. of subjects | ||
Stage 1 | 1,582 | 5,203 |
Stage 2 | 3,525 | 3,642 |
Replication | 2,576 | 5,552 |
Full study population | 7,683 | 14,397 |
Geographic region | ||
United States | 4,387 (57.1) | 7,962 (55.3) |
Central/Northern Europe | 2,264 (29.5) | 3,853 (26.8) |
Southern Europe | 1,032 (13.4) | 2,582 (17.9) |
Sex | ||
Male | 4,107 (53.5) | 8,841 (61.4) |
Female | 3,576 (46.5) | 5,556 (38.6) |
Age, years | ||
≤ 60 | 1,972 (25.7) | 4,577 (31.8) |
61 – 70 | 2,688 (35.0) | 5,906 (41.0) |
> 70 | 3,023 (39.3) | 3,914 (27.2) |
Smoking status* | ||
Current / past | 2,634 (51.6) | 4,541 (51.3) |
Never | 1,642 (32.2) | 3,186 (36.0) |
Unknown | 831 (16.3) | 1,118 (12.6) |
Smoking status was available for subjects in Stages 1 and 2.