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. Author manuscript; available in PMC: 2014 Oct 9.
Published in final edited form as: Psychopharmacology (Berl). 2013 Apr 25;229(2):253–265. doi: 10.1007/s00213-013-3106-9

Figure 2.

Figure 2

Effects of fenobam sulfate on intravenous cocaine self-administration. Oral (p.o) administration of fenobam sulfate significantly inhibited cocaine self-administration (a) and active lever responses (b) in rats. Within-subjects design, n = 11. * p < 0.05, ** p < 0.01 compared to vehicle. It also dose-dependently shifted cocaine dose-response self-administration curve downward (c; vehicle (■), 30 mg/kg (△), 60 mg/kg (○)).Within-subjects design, n = 6. 30 mg/kg fenobam vs. vehicle: ††† p < 0.001; 60 mg/kg fenobam vs. vehicle: * p < 0.05, *** p < 0.001.