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. 2014 Sep 15;111(39):14289–14294. doi: 10.1073/pnas.1407640111

Fig. 2.

Fig. 2.

The 14-mo-old Foxa3-null mice show increased expression of thermogenic and mitochondrial genes in BAT and browning of inguinal fat. (A) Adipose tissue weights of 14-mo-old (14m) WT and Foxa3-null mice. (B) H&E staining of BAT, iWAT, and eWAT of 14-mo-old WT and Foxa3-null mice. (C) Levels of thermogenic and mitochondrial genes in BAT. (D) UCP1 staining in inguinal fat of WT and Foxa3-null mice. (E and F) Levels of thermogenic and mitochondrial genes (E) and of beige fat markers (F) in inguinal fat depots of 14-mo-old (14m) WT and Foxa3-null mice. Data are presented as mean ± SEM. *P < 0.05, **P < 0.01 compared with controls.