Table 2.
Donor ovary genotype | Recipient genotype | Ovary transplant | % of recipients with successful parturition (n) | P value |
Bmal1fx/fx | SF1-Bmal1−/− | Bilateral | 100 (12) | 9e−4* |
SF1-Bmal1−/− | Bmal1fx/fx | Bilateral | 36 (11) | |
Bmal1+/+ | SF1-Bmal1−/− | Unilateral | 100 (3) |
Donor and recipient genotypes are indicated. Numbers in parentheses are number of mice transplanted.
The ratio of successful parturition is significantly higher in recipients with wild type ovaries than SF1-Bmal1−/− ovaries (χ2 test).