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. Author manuscript; available in PMC: 2015 Mar 1.

Published in final edited form as: Nat Rev Urol. 2014 May 13;11(6):317–323. doi: 10.1038/nrurol.2014.91

Incidence of prostate cancer by age group.(A) The age-adjusted incidence of prostate cancer increased dramatically during the late 1980’s and early 1990’s as a result of screening with serum PSA. Since then, incidence has decreased or stabilized among most age groups. Although prostate cancer in men aged ≤55 (early onset prostate cancer or EO) represents only a portion of all men diagnosed with this disease, incidence in this group continues to rise. (B) Incidence in men 50–55 years at diagnosis, among whom screening was commonly recommended by most medical organizations until recently, may have stabilized to some extent, however, (C) among younger men who are not expected to have been screened with PSA, incidence rates continue to rise. (Note the different scale for each chart.)

Incidence of prostate cancer by age group.(A) The age-adjusted incidence of prostate cancer increased dramatically during the late 1980’s and early 1990’s as a result of screening with serum PSA. Since then, incidence has decreased or stabilized among most age groups. Although prostate cancer in men aged ≤55 (early onset prostate cancer or EO) represents only a portion of all men diagnosed with this disease, incidence in this group continues to rise. (B) Incidence in men 50–55 years at diagnosis, among whom screening was commonly recommended by most medical organizations until recently, may have stabilized to some extent, however, (C) among younger men who are not expected to have been screened with PSA, incidence rates continue to rise. (Note the different scale for each chart.)