Skip to main content
. Author manuscript; available in PMC: 2014 Oct 9.
Published in final edited form as: Cancer Res. 2008 Jul 1;68(13):5132–5142. doi: 10.1158/0008-5472.CAN-07-6192

Figure 1.

Figure 1

MYC expression of murine transgenic tumors and human Burkitt’s lymphoma. A, Western blot analysis of MYC proteins in EμSrα-tTA MYC transgenic mice tumors (6814, 6816, 5720, 966, and 6780), Burkitt’s lymphomas (Daudi, Raji, and Jujoye), and normal EBV-transformed lymphocytes (KRA, KRB, and GM). B, mice transplanted with EμSrα-tTA MYC tumors express varying levels of MYC when treated with different concentrations of doxycycline in their drinking water from 0 to 0.5 μg/mL. MYC expression was measured by Western blot analysis. C, EμSrα-tTA MYC tumors transplanted in mice respond differentially to varying levels of doxycycline treatment. Mice were treated with doxycycline in their drinking water (0, 0.05, 0.1, 0.15, 0.2, 0.25, 0.5, and 100 μg/mL) and tumor regression was measured. Changes in tumor size are indicated as percent of original tumor size. See Supplementary Fig. S1 for quantitations.