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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Stroke. 2014 Feb 18;45(4):1012–1017. doi: 10.1161/STROKEAHA.113.004166

Table 4.

Multinomial and ordinal logistic regression results for each retinal disease phenotype, comparing higher scores on the cumulative brain microvascular disease with the lowest possible scores. Adjusted as in Table 2. Odds ratios (95% CI) are displayed. A score of 0–3 is the reference group.

Multinomial logistic regression Unadjusted
ordinal logistic
regression
Adjusted
Ordinal logistic
regression
Retinal finding Score 0–3 Score 5–6 Score 8–9 Score 11–14 OR per higher
category
OR per higher
score category
Any retinopathy 1.0 0.86 (0.25–2.97) 3.57 (1.26–10.13) 4.21 (1.54–11.45) 2.78 (1.63–4.73) 3.18 (1.71–5.89)
AV nicking 1.0 0.57 (0.25–1.29) 1.04 (0.50–2.17) 2.31 (1.26–4.26) 2.65 (1.78–3.94) 1.93 (1.24–3.02)
Focal Arteriolar
Narrowing
1.0 1.71 (0.91–3.21) 2.45 (1.29–4.65) 2.08 (1.12–3.86) 1.92 (1.35–2.73) 1.76 (1.19–2.59)
CRAE/10 1.0 1.00 (0.96–1.04) 0.97 (0.93–1.01) 0.98 (0.94–1.02) 0.99 (0.97–1.01) 0.98 (0.96–1.01)
CRVE/10 1.0 0.99 (0.95–1.04) 1.01 (0.97–1.05) 1.02 (0.98–1.06) 1.00 (0.98–1.02) 1.01 (0.99–1.03)
Microaneurysms 1.0 0.34 (0.05–2.19) 3.24 (0.78–13.38) 3.39 (0.89–12.88) 2.59 (1.29–5.21) 3.06 (1.33–7.07)
Retinal Hemorrhage 1.0 0.92 (0.18–4.74) 2.55 (0.58–11.21) 4.20 (1.07–16.52) 2.85 (1.34–6.06) 3.02 (1.27–7.20)