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. 2014 Oct 9;10(10):e1004637. doi: 10.1371/journal.pgen.1004637

Figure 4. Shared and divergent sequences in related CEHs.

Figure 4

A) A region of nearly identical sequence for the B8,DR3 and B18,DR3 CEHs was previously reported [19] and is represented by the broken line rectangle, and ends just centromeric to MTC30P1, approximately 50 kb centromeric to HLA-DQB1 [18]. B) Shared sequence for the B7,DR15 and B18,DR15 CEHs is shown in the broken line rectangle. Sequence identity for these two CEHs ends centromerically between introns 8 and 6 of TAP2. C) Shared and divergent sequences for four DR4,DQ8 CEHs are shown in the broken line rectangle. HLA-B*15:01 and HLA-B*40:01 are alleles of the B62 and B60 specificities, respectively.