Table 1. MHP cell line and CEH allele-level typing in the core MHC region and HLA-DPB1.
| Class I | Complotype | Class II | ||||||||||
| Cell Line | Conserved Ext. Haplotype | Number Sequenced | HLA-C | HLA-B | CFB | C2 | C4A | C4B | HLA-DRB1 | HLA-DQA1 | HLA-DQB1 | HLA-DPB1 |
| PGF | 07:02 | 07:02 | UNKa | UNK | UNK | UNK | 15:01 | 01:02 | 06:02 | 04:01 | ||
| B7,DR15 | 23 | 07:02 | 07:02 | S | C | 3 | 1 | 15:01 | 01:02 | 06:02 | 04:01 | |
| B18,DR15 | 5 | 12:03 | 18:01 | S | Q0 | 4 | 2 | 15:01 | 01:02 | 06:02 | UNK | |
| COX | 07:01 | 08:01 | S | C | Q0 | 1 | 03:01 | 05:01 | 02:01 | 03:01 | ||
| B8,DR3 | 30 | 07:01 | 08:01 | S | C | Q0 | 1 | 03:01 | 05:01 | 02:01 | 01:01 | |
| QBL | 05:01 | 18:01 | F1 | C | 3 | Q0 | 03:01 | 05:01 | 02:01 | 02:02 | ||
| B18,DR3 | 18 | 05:01 | 18:01 | F1 | C | 3 | Q0 | 03:01 | 05:01 | 02:01 | 02:02 | |
| MANN | 16:01 | 44:03 | F | UNK | Q0 | 1 | 07:01 | 02:01 | 02:02 | 02:01 | ||
| C4,B44,DR7 | 6 | 04 b | 44:03 | F | C | Q0/3 | 1 | 07:01 | 02:01 | 02:02 | UNK | |
| C16,B44,DR7 | 4 | 16:01 | 44:03 | F | C | Q0/3 | 1 | 07:01 | 02:01 | 02:02 | UNK | |
| DBB | 06:02 | 57:01 | S | C | 6 | 1 | 07:01 | 02:01 | 03:03 | 04:01 | ||
| B57,DR7 | 4 | 06:02 | 57:01 | S | C | 6 | 1 | 07:01 | 02:01 | 03:03 | UNK | |
| MCF | 03:04 | 15:01 | UNK | UNK | UNK | UNK | 04:01 | 03 | 03:01 | 04:02 | ||
| B44,DR4,DQ7 | 7 | 05:01 | 44:02 | S | C | 3 | Q0/1 | 04:01 | 03:01 | 03:01 | 04:01 | |
| SSTO | 05:01 | 44:02 | UNK | UNK | UNK | UNK | 04:03 | 03:01 | 03:05 | 04:01 | ||
| B49,DR4,DQ8 | 1 | 07:01 | 49:01 | S | C | Q0 | 1 | 04:05 | 03:01 | 03:02 | UNK | |
| B44,DR4,DQ8 | 6 | 05:01 | 44:02 | S | C | 3 | Q0/1 | 04:01 | 03:01 | 03:02 | 04:01 | |
| B62,SC33,DR4,DQ8 | 8 | 03:04 | 15:01 | S | C | 3 | 3 | 04:01 | 03:01 | 03:02 | 04:01 | |
| B38,SC21,DR4,DQ8 | 9 | 12:03 | 38:01 | S | C | 2 | 1 | 04:02 | 03:01 | 03:02 | 04:01 | |
| B60,SC31,DR4,DQ8 | 10 | 03:04 | 40:01 | S | C | 3 | 1 | 04:04 | 03:01 | 03:02 | 03:01 | |
| B62,SB42,DR4,DQ8 | 7 | 03:03 | 15:01 | S | B | 4 | 2 | 04:01 | 03:01 | 03:02 | 04:01 | |
| APD | 06:02 | 40:01 | UNK | UNK | UNK | UNK | 13:01 | 01:03 | 06:03 | 04:02 | ||
Shown are MHC alleles for the eight MHP cell lines and, underneath each, for the population CEH(s) that share HLA-DR-DQ specificities with them. Although a known CEH shares HLA-DR-DQ specificities with APD, that CEH does not share significant class II sequence similarity to APD, and is not displayed. Genes are in chromosomal order from telomere to centromere, except CFB and C2 are switched because complotype was historically defined in the order shown. HLA gene alleles are shown at the highest definition known up to 4-digit resolution. Alleles containing “/” indicate microvariation.
a
Abbreviations: UNK = Unknown (insufficient data).