Table 2.
Parameter estimates with 95% confidence intervals for the Item Response Theory (IRT) analysis on indicators of alcohol use disorders in a sample of 1336 twin pairs from the general population who have initiated alcohol use.
| Standardized factor loading | Factor loading | Threshold #1 | Threshold #2 | |
|---|---|---|---|---|
| Life-time DSM-IV alcohol dependence | 0.95 (0.91 – 0.99) | 5.24 (3.18 – 7.30) | 6.52 (4.23 – 8.81) | - |
| Life-time DSM-IV alcohol abuse | 0.83 (0.78 – 0.88) | 2.65 (2.14 – 3.16) | 3.96 (3.42 – 4.51) | - |
| Binge drinking: ≥5 units | 0.65 (0.60 – 0.70) | 1.56 (1.35 – 1.77) | 1.12 (0.94 – 1.29) | 3.46 (3.19 – 3.73) |
| Self-perceived life-time alcohol abuse | 0.65 (0.60 – 0.71) | 1.58 (1.35 – 1.77) | 1.06 (0.89 – 1.24) | 2.01 (1.80 – 2.22) |
Mean for men on the AUD risk continuum was fixed to zero, and estimated to be −0.65 (−0.77 to −0.52) for women. The variance of AUD risk continuum was not different across sex, and fixed to unity. The factor loading is the increase in log-odds for the category with an increase on the factor of 1. The first threshold is the log-odds for the category when the factor is at zero. The second threshold is the increase in log-odds beyond threshold 1 for the category when the factor is at zero. The standardized factor loading is the correlation between the latent factor and the observed categorical indicator. All estimates are given with ± standard error. Thresholds for binge drinking were (#1) ‘2–4 times per month’ and (#2) ‘1–2 times per week’ or ‘more often’. For self-perceived life-time alcohol abuse, the thresholds were (#1) ‘maybe’ and (#2) ‘yes’.